Eric Eckert2 more U.S. soldiers develop severe pneumoniaSat Aug 2 20:25:27 200364.140.158.107August 1, 20032 more U.S. soldiers develop severe pneumonia, put on ventilatorsBy Eric EckertNews-Leader Staff http://www.news-leader.com/today/0801-2moreUSsol-123700.html Two more U.S. soldiers serving in the Middle East were placed on ventilators this week after developing severe pneumonia, Army officials said Thursday.Since March 1, approximately 100 troops have been afflicted with the illness, according to a news release from the Army Surgeon General. Of those cases, 14 have been placed on respirators and two have died — including Missouri National Guard Spc. Joshua Neusche of Montreal, in Camden County."The 14 cases were geographically dispersed and came from different units," the release stated, adding there's no evidence soldiers were exposed to chemical or biological weapons, environmental toxins or severe acute respiratory syndrome (SARS).Neusche's parents, Mark and Cynthia Neusche, say doctors told them their son's liver, kidneys and muscles broke down — occurrences the surgeon general's office say are rare in cases of pneumonia."There's definitely something out there," Mark Neusche said Friday. "We need to find out what it is and get it fixed. The numbers are climbing."The Army has deployed two epidemiology units to study the outbreak. One team has been sent to the Landstuhl Regional Medical Center in Germany, where the majority of the severe cases have been treated. The other team will be sent to undisclosed areas of Iraq. The teams are looking for similarities among the cases.The surgeon general's office says young, healthy soldiers dying from pneumonia is rare, but does occur. From 1998 to 2002, 17 soldiers have died from pneumonia or complications from the illness-------------------------------------------------Duluth News Tribune (MN) 1 Aug 2003 [edited] http://www.duluthsuperior.com/mld/duluthsuperior/news/6437091.htm Army Sends Teams to Probe Iraq Illness--------------------------The Army is trying to figure out what is causing a rash of serious pneumonia cases, including 2 fatalities, among soldiers serving in Iraq.A 6-person team of specialists was en route to Iraq today to investigate 14 cases of pneumonia serious enough that the soldiers had to be put on ventilators to breathe and evacuated from the region, the Army Surgeon General's office said Fri, 1 Aug 2003. “2 soldiers died, 9 recovered, and 3 were still hospitalized as of Thu, 31 Jul 2003,” spokeswoman Lyn Kukral said.The team on its way to Iraq includes infectious disease experts, laboratory officers, and people who will take samples of soil, water, and air.So far, officials have identified no infectious agent common to all the cases. There is no evidence any of the cases were caused by exposure to chemical or biological weapons, environmental toxins or Severe Acute Respiratory Syndrome (SARS), officials said.A 2-person team already has gone to Landstuhl Regional Medical Center in Germany, where most of the cases were treated after evacuation. The 2 teams also will review patient records and laboratory results and interview health care workers and patients, if possible, said a statement from the Army Surgeon General and U.S. Army Medical Command.The teams will be looking for similarities among the cases, which so far have hit troops in geographically dispersed areas and from different units, said the Thursday statement. They also were spread over time, with 2 in March, 3 in April, 2 in May, 3 in June, and 4 in July [2003].Though only 14 cases were considered serious, there have been 100 cases altogether since 1 Mar 2003 among troops that began deploying in late 2002 to the Persian Gulf.Army-wide, pneumonia cases serious enough to warrant hospitalization happen in about 9 of 10 000 soldiers per year. Given the number of troops deployed, the 100 cases "do not exceed expectations," the surgeon general's office said.[Byline: Pauline Jelinek]-------------------------------------------------ProMED-mail[The information above suggests that the cases were spread out geographically and over time, but no information is given with regard to common factors.While a recognized bioterror agent such as botulinum toxin can cause respiratory failure, it is due to a neuromuscular problem, not pneumonia per se. If no bacteria were isolated from respiratory and, perhaps, surgical or postmortem specimens, then unless the organism is fastidious -- as _Legionella pneumophila_ is -- the illness seems not to be bacterial. Acute fungal pneumonitis due to histoplasmosis or coccidioidomycosis could present in this way if those organisms or something similar were found in the soil. Histopathology and cultures would be helpful in this regard. Certainly, a viral etiology requires strong consideration. [ProMED understands that histopathology is being carried at AFIP - the U.S. Armed Forces Institute of Pathology - Mod.JW]No information is given regarding prodromal symptoms and possible incubation periods, so speculation regarding toxin exposures such as phosgene, chlorine, or paraquat, or metals such as manganese or cadmium is just that -- speculation.Hopefully, more information about the cases will become available, and the outbreak curve will diminish.Regarding _Burkholderia mallei_, brought up in the previous posting in this thread, an additional point is relevant. Although not fastidious, identifying the bacillary agent responsible for glanders can be difficult, since automated identification systems may misidentify it.- Mod.LL]
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