Charles Ostman Index:
http://www.historianofthefuture.com/
The NanoBiology Imperative
http://www.historianofthefuture.com/nanobio.html
All living things are nanofoundries. Nature has
perfected the artform of biological nanotechnology for
billions of years. Now, an emerging technology domain is
poised to present a toolkit from which new lifeforms can
be crafted, the inner molecular workings of living cells
can be directly manipulated, even aging may be treated
not as a disease, but as a reversable pathology. The
very definition of life itself is perched at the edge of
the next great revolution in medicine: nanobiology.
Currently existing are technologies and applications in
the arenas of biomolecular components and biocompatible
surfaces integrated into microscale systems, implantable
biochip devices, synthetically engineered quasi-viral
components, modified DNA, structured proteomics,
pseudoproteins, biomolecular "devices". What is coming
are artificially engineered organelles and cells,
technologies which combine organic and inorganic
materials and substrates into integrated nanoscale
systems, "biomolecular prosthetics", and intra-cellular
modification strategies which will redefine the very
essense of what is commonly referred to as life.
The worlds of biotechnology and nanotechnology currently
converge into nanobiology. The first patents for
utilizing a modified virus as a proteomic delivery
vehicle, that being a molecular scale "device" which can
seek out specific cells and deliver various materials to
the inner parts of those cells, were issued to Onyx
pharmaceuticals in 1996. In 1997, the Nanobiological
Systems Group of Searle Labs (a division of Monsanto
Chemical) was using dendrimer molecules, a sort of
complex nanoscale branching structure which can be
"grown" into very specific geometric forms, as another
type of cellular targeting and delivery system. These
same dendrimer molecules also are part of a growing
collection of self-assembling and self organizing
"components", the leggo blocks of nanotechnology. Now
several companies have emerged into the marketplace with
their versions of these dendrimer molecular systems.
Molecular protein delivery to targeted, specific cell
types is currently being developed as a method for
instigating physiological adjustment or modifications
within living cells. In this context, protein can be
viewed as being the functional equvilant of "software"
which instructs the activities of biomolecular
mechanisms and organelles within the cell, somewhat in
the same way that machine code instructs computer
processor chips to perform various functions. Among many
such examples of this process being currently studied,
is the utilization of the P53 protein, which can act
like a "switch" to literally shut down the metabolism of
a living cell. This has potential, for instance, as a
possible cure for various forms of cancer, in that the
cancer cells have a genetic identity different than the
original cell types from which they emanated, and
therefore can be "targeted" for delivery of this P53
protein.
http://www.historianofthefuture.com/nanobio.html
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Carbon nanotubes offer 'green' technology for
perchlorate removal. Researchers at Pacific Northwest
National Laboratory have demonstrated a new,
environmentally friendly process for treating water
contaminated by perchlorate, a toxic chemical that has
been found in drinking water in 35 states. Physorg
7.25.06
Nanotechnology being used to improve biocompatibility of
human prosthetics and implants. As populations of the
world age the current trend is that people are not
slowing down in their later years. The desire for
increased activity among the elderly also means
increased demands on medical researchers to come up with
better ways to keep them active. A2Z 8.2.06
http://www.nanoindustries.com/